Since starting the 2020 season at 11-0, the Pittsburgh Steelers have now lost eight of their last 10 games including the playoffs, and NFL pick’em players who haven’t caught on to the trend have been left in the dust. Ben Roethlisberger looks like a shell of his former self playing behind a struggling offensive line. He’ll have his work cut out again on Sunday against a Broncos defense that has 11 sacks and 23 quarterback hits in four games. Should your NFL office pool picks involve backing Von Miller and Denver in this Week 5 matchup or can the Steelers finally get back on track?

The Cardinals look like they’re turning the corner as one of the NFL’s best and enter Week 5 as the only unbeaten team remaining in the NFL. Should you back them against the 49ers in your Week 5 NFL pool picks, and how many points should you assign in your NFL confidence pool picks? Before you make your NFL predictions, you need to see the Week 5 NFL football pool picks from SportsLine’s proven model.

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception six years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 5 of the 2021 season on an incredible 124-82 run on top-rated NFL picks that dates back to the 2017 season.

More importantly for NFL confidence pool players, the model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports office pool players four times during that span. Anyone who has followed it is way up.

Now, the model has simulated the entire Week 5 NFL schedule 10,000 times and generated its optimal NFL pick’em plays. Go to SportsLine to see them.

Top Week 5 NFL office pool predictions

One of the top Week 5 NFL pick’em predictions from the model: The Cowboys cruise past the Giants for a comfortable nine-point win.

With quarterback Dak Prescott back from a gruesome ankle injury, the Cowboys’ offense has lived up to the hype as one of the most dynamic units in the NFL and are coming off arguably their best performance of the year. The Panthers were the No. 1 defense in the NFL entering Week 4, but the Cowboys still managed to pile up 433 yards of total offense and to score 36 points in an impressive win.

Dallas is now 3-1, with its only loss coming on a field goal as time expired to the defending champion Buccaneers in Week 1. The Giants are coming off their first win of the season, but with a defense that has given up at least 400 total yards to three of four opponents this year, they’re going to have to match Dallas’ offense score for score to stay in the game.

Daniel Jones’ propensity for turning the ball over puts the Giants at a natural disadvantage in a shootout, and the model is predicting a couple of Giants giveaways plague the visitors. It also predicts Prescott throws for over 300 yards and two touchdowns to help the Cowboys win in nearly 70 percent of simulations with a projected final score of 32-23.

How to make Week 5 NFL office pool picks

The model also made the call on every other Week 5 game and has strong picks for potentially close matchups like Bills vs. Chiefs and Packers vs. Bengals. It’s also calling for multiple underdogs to win outright. You can only see all of the model’s NFL pool picks here.

So who should you pick in every Week 5 NFL game? And which underdogs win outright? Visit SportsLine now to get optimal NFL office pool picks, all from the advanced computer model that has ranked in the Top 10 on straight-up picks four of the last five years and went an outstanding 124-82 on top-ranked picks since 2017 .


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